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  1. REMERON has an elimination half-life of approximately 20 to 40 hours

    References Croom, Katherine F. Kast, R. Adjunct mirtazapine for negative symptoms of schizophrenia.

    Hannan, Noel, et al. So, as a conclusion even though the combination of mirtazapine with venlafaxine makes pharmacological sense, the evidence is limited to case reports.

    Pharmacokinetics Mirtazapine has a half-life of 20 to 40 hours. Mirtazapine is remeron indications only for depression. However, it is a serotonergic and noradrenergic antidepressant, this is because mirtazapine blocks receptors that modulate release of these neurotransmitters.

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    Mirtazapine blocks serotonin remeron indications, in this image the 5HT3 receptor is shown. Mirtazapine disinhibits serotonergic neurons in the dorsal raphe, leading to increased serotonin release in the cortex.

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    Mirtazapine is an interesting option for depressed patients suffering from chemotherapy induced nausea and vomiting - remeron tremor.

    . Mirtazapine is commonly used in the elderly population and Because of its histamine 1 antagonist properties mirtazapine is sometimes used for the treatment of insomnia.

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